Interferon-α action in cytokine profile in eosinophilic nasal polyp cultures
نویسندگان
چکیده
منابع مشابه
Inflammatory Septal Nasal Polyp
Introduction: Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma. Aetiology is multifactorial and is mainl...
متن کاملStaphylococcus aureus superantigens and their role in eosinophilic nasal polyp disease.
Nasal polyposis is a chronic disease of the upper airways which adversely affects the quality of life of patients. Its pathophysiology is still unclear. Recently, several studies have shown different inflammatory pathways which relate to both innate and adaptive immune responses. Moreover, different phenotypes may exist in different ethnic groups of patients. This article will review recent dat...
متن کاملFungal extracts detected in eosinophilic chronic rhinosinusitis induced cytokines from the nasal polyp cells
OBJECTIVES/HYPOTHESIS The role of fungi in chronic rhinosinusitis (CRS) is still controversial. The present study was conducted to detect and identify fungal species from the nasal polyp tissues of eosinophilic and noneosinophilic CRS, and to determine the role of fungal antigens in cytokine production. STUDY DESIGN Prospective study. METHODS Thirty-five specimens of nasal polyps were colle...
متن کاملInflammatory Septal Nasal Polyp
INTRODUCTION Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma. Aetiology is multifactorial and is mainly a...
متن کاملProteasome inhibition reduces proliferation, collagen expression, and inflammatory cytokine production in nasal mucosa and polyp fibroblasts.
Proteasome inhibitors, used in cancer treatment for their proapoptotic effects, have anti-inflammatory and antifibrotic effects on animal models of various inflammatory and fibrotic diseases. Their effects in cells from patients affected by either inflammatory or fibrotic diseases have been poorly investigated. Nasal polyposis is a chronic inflammatory disease of the sinus mucosa characterized ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2021
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2019.08.010